Responses to Drug-Induced Myocardial Necrosis in Rats with Various Degrees of Arteriosclerosis

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Responses to drug-induced myocardial necrosis in rats with various degrees of arteriosclerosis.

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• Acute infarctoid myocardial necrosis can be produced in virgin rats by injection of the potent catecholamine, isoproterenol. We have noted that these myocardial lesions are essentially identical, both grossly and microscopically, to acute infarcts which occur spontaneously in the hearts of breeder rats with arteriosclerosis."" Rats with drug-induced myocardial necrosis show signs of shock whi...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1967

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.20.1.78